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    Guiding Principles for Ethical Research

    “When people are invited to participate in research, there is a strong belief that it should be their choice based on their understanding of what the study is about, and what the risks and benefits of the study are,” said Dr.

    Christine Grady, chief of the NIH Clinical Center Department of Bioethics, to Clinical Center Radio in a podcast.

    Clinical research advances the understanding of science and promotes human health.

    What are the 7 principles of ethics in research

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  • However, it is important to remember the individuals who volunteer to participate in research. There are precautions researchers can take – in the planning, implementation and follow-up of studies – to protect these participants in research.

    Ethical guidelines are established for clinical research to protect patient volunteers and to preserve the integrity of the science.

    NIH Clinical Center researchers published seven main principles to guide the conduct of ethical research:

    • Social and clinical value
    • Scientific validity
    • Fair subject selection
    • Favorable risk-benefit ratio
    • Independent review
    • Informed consen

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